Vendor source

Reviewed 16 Oct 2026

Completeness Strong (69%)

HeartFlow FFRCT Analysis

HeartFlow

The HeartFlow Analysis is a coronary physiologic simulation software for the clinical quantitative and qualitative analysis of previously acquired Computed Tomography DICOM data for clinically stable symptomatic patients with coronary artery disease. It provides the calculations of FFRCT, a mathematically derived quantity, computed from simulated pressure, velocity and blood flow information obtained from a 3D computer model generated from static coronary CT images. The HeartFlow Analysis is intended to support the functional evaluation of coronary artery disease.

Supported by 19 papers

HeartFlow FFRCT Analysis thumbnail 1
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Key Features

  • FFRCT values along coronary vessels

General Information

Product name

HeartFlow FFRCT Analysis

Company

Modality

CT

Main task

Not specified

Subspeciality

Cardiac

Disease targeted

Coronary artery stenosis, coronary artery disease

Regulatory Information

CE Certification

Pathway:

MDD

Class:

Class IIa

Verified by Health AI Register

FDA Certification

Pathway:

510(k) cleared

Class:

Class II

Verified by Health AI Register

Other certifications

Not specified

Evidence & Research

Peer-Reviewed Papers

Developing a non-invasive diagnostic framework for the fractional flow reserve quantification in left coronary arteries: validation with patient cases

Frontiers in Physiology · Jul 2026

Coronary plaque burden and computed tomography-derived fractional flow reserve are predictors of 5-year mortality in peripheral artery disease patients with no known coronary artery disease

Journal of Vascular Surgery Cases, Innovations and Techniques · Jun 2026

Impact of an interactive CTCA/FFRCT interventional stent planning tool on patient management

The International Journal of Cardiovascular Imaging · Jul 2025

Implementation of a national AI technology program on cardiovascular outcomes and the health system

Nature Medicine · Apr 2025

Diagnosis and treatment of ischemia-producing coronary stenoses improves 5-year survival of patients undergoing major vascular surgery

Journal of Vascular Surgery · Mar 2024

Long-term prognostic implications of CT angiography-derived fractional flow reserve: Results from the DISCOVER-FLOW study

Journal of Cardiovascular Computed Tomography · Feb 2024

Computed tomography-derived fractional flow reserve (FFRCT) has no additional clinical impact over the anatomical Coronary Artery Disease - Reporting and Data System (CAD-RADS) in real-world elective healthcare of coronary artery disease

Clinical Radiology · Aug 2022

Impact of Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography on Heart Team Treatment Decision-Making in Patients With Multivessel Coronary Artery Disease

Circulation: Cardiovascular Interventions · Dec 2019

1-Year Impact on Medical Practice and Clinical Outcomes of FFRCT

JACC: Cardiovascular Imaging · Mar 2019

Comparison of Coronary Computed Tomography Angiography, Fractional Flow Reserve, and Perfusion Imaging for Ischemia Diagnosis

Journal of the American College of Cardiology · Jan 2019

Coronary CT Angiographic and Flow Reserve-Guided Management of Patients With Stable Ischemic Heart Disease

Journal of the American College of Cardiology · Aug 2018

Real-world clinical utility and impact on clinical decision-making of coronary computed tomography angiography-derived fractional flow reserve: lessons from the ADVANCE Registry

European Heart Journal · Aug 2018

Identification of High-Risk Plaques Destined to Cause Acute Coronary Syndrome Using Coronary Computed Tomographic Angiography and Computational Fluid Dynamics

JACC: Cardiovascular Imaging · Mar 2018

Effect of the ratio of coronary arterial lumen volume to left ventricle myocardial mass derived from coronary CT angiography on fractional flow reserve

Journal of Cardiovascular Computed Tomography · Aug 2017

Computed tomography derived fractional flow reserve testing in stable patients with typical angina pectoris: influence on downstream rate of invasive coronary angiography

European Heart Journal - Cardiovascular Imaging · Mar 2017

1-Year Outcomes of FFRCT-Guided Care in Patients With Suspected Coronary Disease

Journal of the American College of Cardiology · Jul 2016

Quality-of-Life and Economic Outcomes of Assessing Fractional Flow Reserve With Computed Tomography Angiography

Journal of the American College of Cardiology · Oct 2015

Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR<sub>CT</sub>: outcome and resource impacts study

European Heart Journal · Sep 2015

Diagnostic Performance of Noninvasive Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography in Suspected Coronary Artery Disease

Journal of the American College of Cardiology · Jan 2014

Technical Specifications

Patient population age

Not specified

Input

Coronary CT (following SCCT and ACC guidelines), 64-slice or higher

Input format

DICOM

Output

3D model of coronary tree with FFRCT values

Output format

3d model, PDF

Integration

Integration in standard reading environment (PACS), Integration with HL7, Stand-alone webbased

Deployment

Cloud-based

Trigger for analysis

On demand, triggered by a user through e.g. a button click, image upload

Processing time

Not specified

Population

People with suspected coronary artery disease

Market Presence

On market since

01-2016

AI Platforms

Resellers

Not specified

Countries present

Not specified

Paying clinical customers

>500

Research/test users

Not specified

Pricing Information

Pricing model

Not specified

Based on

Number of analyses

Source: Vendor | First published: Jun 9, 2024 | Last updated: Oct 16, 2026